产品货号:
Z35000
中文名称:
Lamin A/LMNA抗体
英文名称:
Anti-Lamin A/LMNA Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Lamin A/LMNA Antibody |
指标别名 | 70kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;HGPS;IDC;lamin A;lamin A/C;LDP1;LFP;LGMD1B;LMN1;LMNA;LMNC;Prelamin A/C;PRO1;progerin |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ELISA |
基因名称 | LMNA |
克隆号 | 40000000 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of human Lamin A expressed in E.Coli. |
计算分子量 | 74KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Lamins are structural protein components of the nuclear lamina,a protein network underlying the inner nuclear membrane that determines nuclear shape and size.There are three types of lamins,A,B and C.The lamin A/C (LMNA) gene contains 12 exons.Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and lamin C.Lamin A/C is mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy,dilated cardiomyopathy,and Hutchinson-Gilford progeria syndrome.Lamin A/C deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription. |
Uniprot ID | P02545 |
基因名全称 | Prelamin-A/C |
蛋白名全称 | Prelamin-A/C |
推荐稀释比 | WB 1:500~1:2000 IHC 1:200~1:1000 ELISA 1:10000 |
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